Arsenal and Real Madrid have previously met twice in the Champions League and the Gunners have the overall edge.

Arsenal and Real Madrid are set to clash in the Champions League for the first time in 19 years.

Arsenal and Real Madrid might be two of the biggest clubs in the world, but they have rarely come face to face. In fact, the two sides have only played one another twice in the history of the Champions League.

Despite Real Madrid's dominance in the competition, Arsenal have the head-to-head edge over the Spanish giants thanks to club legend, Thierry Henry. Real Madrid, though, have a record 15 Champions League titles in their trophy cabinet while the Gunners have zero.

History aside, the two clubs will meet again for the first time since 2006 in this year's Champions League quarterfinals. Bukayo Saka and Kylian Mbappé headline the long list of superstars set to feature in the match, but only one team will punch their tickets to the Champions League semifinals.

The first time Real Madrid and Arsenal ever faced off, Henry left the Santiago Bernabéu with the only goal of the match. The Frenchman received the ball at midfield and dribbled past three white shirts on his charge into the box. Sergio Ramos's last-ditch tackle did nothing to stop Henry from firing a left-footed strike past Iker Casillas and into the back of the net.