Sithokozile Chamisa, formerly Sithokozile Nyaradzo Thabethe, came into the limelight on February 28, 1978, establishing herself as a prominent figure in Zimbabwe as a respected lawyer and humanitarian. While she is widely recognized as the wife of Nelson Chamisa, the dynamic leader of the opposition party Citizens Coalition for Change (CCC) and a notable presidential candidate in the 2018 elections, Sithokozile has carved out her own distinctive identity and legacy in the realms of law, women's rights advocacy, and community development.

Though Sithokozile's public persona is intrinsically linked to her husband's political trajectory, she has diligently cultivated her own professional standing and social impact, championing causes close to her heart such as women's rights and active civic engagement. Her unwavering dedication to legal principles and social justice has earned her widespread acclaim and reverence within Zimbabwe's legal and humanitarian spheres, underscoring her multifaceted contributions to societal well-being and gender equality.

Sithokozile's foray into the public sphere unfolded in May 2018 when Nelson Chamisa proudly introduced her to his ardent supporters at a monumental rally, shedding light on her preference for a more private and understated existence, focusing on nurturing their family life behind the scenes. Despite the glare of her husband's political spotlight, Sithokozile has consciously opted for a low-key presence, prioritizing her pivotal roles as a devoted wife, nurturing mother, and committed advocate for social justice and human rights.