It's not always possible to prevent high bilirubin in infants or adults, but there are a few ways to lower the risk.

In general, people can prevent high bilirubin levels by addressing its underlying causes, such as obstructions or liver disease.

In addition, eating a healthy diet full of whole grains, fruits, and vegetables, and getting regular exercise is associated with decreased risk of gallstones, which are a common cause of elevated bilirubin.

In people who have Gilbert syndrome, excessive stress and dehydration can trigger high bilirubin, says Kwok. Managing stress may help keep bilirubin levels down.