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The Best Custom Skin-Care Brands Cater to Your Biggest Concerns
May 21, 2025
They can also be an easy way to get prescription-strength actives without leaving the house.
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With so many cleansers, moisturizers, and face serums on the shelves, it can be hard to know which products are right for you. That’s where the best custom skin-care brands come in. Not only will custom formulas cater to your skin type, preferences, and concerns but they’ll also give you access to prescription-strength actives that would normally require a doctor’s visit—not to mention time spent in the waiting room that you’ll never get back.
Whether you’re looking for a prescription-strength serum to minimize fine lines, a personalized body wash, or a skin trio tailored to rosacea or acne, we’ve got you covered with custom skin care brands that do it all. It’s never been easier to take great care of your skin!
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Best for Overall: Agency by Curology
Agency by Curology
Dark Spot Formula
Why it’s worth it:Agency is like having a dermatologist on speed dial—except better, because it doesn’t involve talking on the phone. After sending photos of your skin and filling out an easy online form detailing your concerns, skin-care routine, and medical history, you’ll get matched with a licensed dermatology provider who can create a custom treatment plan for you. The pinnacle of your plan will be the Best of Beauty-winning Future Formula, a cream your dermatology provider will customize with ingredients—tretinoin, niacinamide, azelaic acid, to name a few options—they recommend for your skin’s needs.
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